Customized assays can be developed upon request.
- Accurately measures total protein levels, protein-protein interactions, or phosphorylated proteins.
- Increased sensitivity over alternative protein biomarker technologies such as immunochemistry (IHC).
- Provides a continuum of protein expression levels over a wide dynamic range.
- Validated analytical assays available or consultation with scientific staff for fit-for-purpose assay development.
- For use in formalin-fixed paraffin-embedded cell lines, xenografts, human tissues, and peripheral blood mononuclear cells (PBMCs).
VeraTag technology provides pharmaceutical partners and academic collaborators with sensitive and quantitative measurements of protein-protein complexes, activated proteins, and cell-surface receptors in formalin-fixed paraffin-embedded (FFPE) cell lines, xenografts, and human tissues.
Research, Preclinical, and Clinical Trial Services Available
Services for clinical trials include:
- Early development, pharmacodynamic, and mechanism-of–action (MOA) studies.
- Biomarker detection and quantification in tumors and blood samples (PBMCs).
- Correlation with outcome in retrospective or prospective clinical studies.
- Patient stratification utilizing a quantitative measurement of biomarker(s).
- Companion diagnostics to guide treatment selection of patients with targeted therapy.
Benefits of Monogram services and capabilities:
- On-site, fully licensed, CLIA/CAP certified clinical reference laboratory.
- Streamlined, analytically validated, and quality controlled assays.
- Knowledgeable scientific, clinical, and project management staff. We have published more than 24 peer-reviewed articles on VeraTag technology.
- Support from Covance, Inc.'s drug development and companion diagnostics teams.
- Companion diagnostics to guide treatment selection of patients with targeted therapy.
For more information, contact us.