How does the HERmark test work?

The HERmark breast cancer assay is based on VeraTag® technology. HERmark quantitatively measures HER-2 total protein using a dual antibody format, whereby a fluorescent tag on one analyte-specific antibody is cleaved when in close proximity to a second antibody containing a photoactivated molecule. The fluorescent tags are then quantified using capillary electrophoresis (CE).