Monogram Biosciences' PhenoScreen™ is a phenotypic screening assay designed to evaluate the activity of reverse transcriptase (RT), integrase, or entry inhibitors in a high throughput fashion. At this time it is not possible to evaluate Protease Inhibitor compounds with PhenoScreen. This assay is an economical way to screen many compounds (typically greater than 25) against a small panel of well-characterized library viruses. The virus panel, which is selected based on client's requirements, consists of 5 to 20 viruses and is used repeatedly for all compounds tested. The reported data consist of IC50 and Fold Change values compared to a wild-type reference HIV-1 virus and susceptibility curves for each drug/virus combination.

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For more information on Monogram assays, services and pricing, please contact us.